This paper addresses online and open education. It presents a simple, yet comprehensive framework that can be adopted by any higher education institution in seek of: (1) clarification of terms and concepts related to online and open education, (2) awareness of issues and challenges to set up strategies for online or open learning, (3) informed choices and their impacts on operationalization actions, from an institutional point of view, (4) perspectives on crucial issues, such as mobility, that HEI faces in a context of internationalization, (5) awareness of policymakers and teachers on what open and online education is.